Moderate Coffee Consumption and Cardiovascular Health:  Literature Review of Benefits, Risks and Individual Variations

Achmad Hendra Hartawan Wawan

doi:10.54518/rh.4.5.2024.452

Authors

Achmad Hendra Hartawan Wawan Departement of Biomedical Sciences, Faculty of Medicine, Surabaya University, Surabaya, Indonesia

DOI:

https://doi.org/10.54518/rh.4.5.2024.452

Keywords:

Coffee, Cardiovascular Health, Caffeine, Inflammation, Metabolic Health

Abstract

The study aims to evaluate the relationship between coffee consumption and cardiovascular risk by using literature review approach. The findings reveal that moderate coffee consumption has been associated with various cardiovascular benefits, including reduced mortality and improved metabolic health, particularly among individuals with healthy lifestyles and without pre-existing conditions such as hypertension or metabolic syn-drome. Bioactive compounds in coffee, including caffeine, phenolic acids, and antioxidants, contribute to these benefits by reducing inflammation, enhancing vascular function, and improving insulin sensitivity. However, excessive coffee consumption can have adverse cardiovascular effects, such as elevated blood pressure and increased risk of arrhythmias, especially in individuals with hypertension or genetic predispositions to caffeine sensitivity. Genetic factors, such as variations in the CYP1A2 gene affecting caffeine metabolism, further modulate individual responses to coffee. This highlights the need for personalized recommendations that consider genetics, health status, and consumption patterns to optimize coffee’s cardiovascular benefits. Additionally, understanding the timing of coffee intake in relation to individual metabolic rhythms may further enhance its health-promoting potential.

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References

Bhandari, B., Zeng, L., Grafenauer, S., Schutte, A. E., & Xu, X. (2024). Long-term consumption of 6 different beverages and cardiovascular disease-related mortality: A systematic review and meta-analysis of prospective cohort studies. Current Developments in Nutrition, 8(3), 102095.

Chen, L., Wu, X., & Wang, P. (2024). Coffee consumption during pregnancy increases the risk of preeclampsia in rats by inhibiting 2-methoxyestradiol production. Biology of Reproduction, 111(5), 1129–1141.

Farber, J., Dikdan, S., Ruge, M., Johnson, D., & Shipon, D. (2024). Relationship between caffeine consumption and young athletes’ comorbidities, exercise-related symptoms, and baseline electrocardiogram. Sports Health, 16(3), 448–456.

Han, S., Qiu, Y., Zhang, G. Q., Lian, F., & Zhang, W. (2024). A meta-analysis and systematic review of randomized clinical trials on the effect of coffee consumption on heart rate. Nutrition Reviews, 82(8), 1046–1055.

Hsieh, P.-C., Nfor, O.N., Lin, C.-C., Hsiao, C.-H., & Liaw, Y.-P. (2024). Metabolic syndrome risk in adult coffee drinkers with the rs301 variant of the LPL gene. Nutrition Journal, 23(1), 30.

Karagöz, M. F., Koçyiğit, E., Koçak, T., Özturan Şirin, A., Icer, M. A., Ağagündüz, D., & Coreta‐Gomes, F. (2024). Decoding coffee cardiometabolic potential: Chemical composition, nutritional, and health relationships. Comprehensive Reviews in Food Science and Food Safety, 23(5), e13414.

Qi, J., Zhang, K., Zhang, P., Lu, Y., & Zhu, X. (2024). Habitual coffee and tea consumption and risk of cataract: A prospective cohort study from the UK Biobank. Clinical Nutrition ESPEN, 62, 81–87.

Quarti-Trevano, F., Facchetti, R., Cuspidi, C., Mancia, G., & Grassi, G. (2024). Habitual coffee consumption and risk of cardiovascular and all-cause mortality in the PAMELA hypertensive population. Nutrition, Metabolism and Cardiovascular Diseases, 103776.

Setia Santoso, L. F. A., Nasr, K., Roumani, A. M., Abou Zeid, H. K., & Dabbous, M. S. (2024). Unraveling tea and coffee consumption effects on cardiovascular diseases risk factors: A narrative review. Health Science Reports, 7(9), e70105.

Sun, D., Gao, Y., Xu, B., Luo, H., Wu, I.X.Y., & Zhang, Z. (2024). Association of coffee consumption with cardiometabolic multimorbidity: A prospective cohort study in the UK biobank. Nutrition, Metabolism and Cardiovascular Diseases, 34(12), 2779–2788.

Ungvari, Z., & Kunutsor, S. K. (2024). Coffee consumption and cardiometabolic health: a comprehensive review of the evidence. GeroScience, 46(6), 6473-6510.

Wen, J., Du, L.-L., Pan, Q., Zhou, H., & Tang, Y.-D. (2024). Association of coffee consumption with atherosclerotic cardiovascular disease and all-cause mortality in adults with familial hypercholesterolemia: Results from National Health and Nutrition Examination Survey (NHANES). Nutrition Clinique et Metabolisme, 38(1), 27–35.

Yang, R., Lei, Q., Liu, Z., Wei, W., & Han, T. (2024). Relationship between timing of coffee and tea consumption with mortality (total, cardiovascular disease and diabetes) in people with diabetes: The U.S. National Health and Nutrition Examination Survey, 2003–2014. BMC Medicine, 22(1), 526.

Zhang, S., Xiang, B., Su, X., Zhao, Y., & Zhou, X. (2024). Is coffee, tea, and red wine consumption beneficial for individuals with hypertension? Postgraduate Medical Journal, 100(1186), 603–610.

Zhou, H., Nie, J., Cao, Y., Zhang, Z., Li, B., & Zhang, L. (2024). Association of daily sitting time and coffee consumption with the risk of all-cause and cardiovascular disease mortality among US adults. BMC Public Health, 24(1), 1069.

Zhu, Y., Hu, C.-X., Liu, X., Zhu, R.-X., & Wang, B.-Q. (2024). Moderate coffee or tea consumption decreased the risk of cognitive disorders: An updated dose-response meta- analysis. Nutrition Reviews, 82(6), 738–748.